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Lipid Metabolism Pathway

How does ChREBP work with other genes in its class to regulate transcription of target genes?

ChREBP being the gene found in mice relating to the communication between the pathways for glucose and lipid metabolism.

ChREBP along with a Max-like factor X (Mlx) binds to the carbohydrate response element (ChoRE). ChoRE is a sequence found in the promotor region of many genes involved in glucose metabolism.

4PBA a Potential Anti-Fat Drug – Austin Laboratory, Hamilton, ON


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