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Bilirubin Metabolism

February 23rd, 2010 Leave a comment Go to comments

Liver medical scenario question?

A man walks into your GP surgery (doctors surgery) and shows the following symptoms:

Yellow Skin to do with bilirubin.

The blood sugar level all over the place to do with carbohydrate metabolism.

Fatty meals make him ill to do with bile production>

Suggest with biological explanation, what is wrong with him>

Thanks
if possible need to explain reasons for each sympton thanks

Bilirubin is made from the break down of
our dead red blood cells. It is in a non
soluble form until it reaches the liver on
a protein known as Albumin. The liver
breaks it down into a soluble form to
flow with the bile to the outside of
the liver ..through tube like structures,
known as ducts, to the intestines to
help in the digestion of fats we eat.

Anything that blocks this flow of bile
to the intestines can cause problems
such as you mentioned.

A gallstone moving out into the ducts
can block the flow of bile to the intestines
and also back it up into the liver. The
bile backing up into the liver can cause
cells damage and inflammation to start
to develop. The bilirubin, which is part of
the bile, may stay in the blood or not
be broken down into a soluble form.
Bilirubin is a pigment…normally
brownish green in color. If it is in the
blood in excess, it can cause the
yellowing of the skin, mucous membranes,
and the white of the eyes and also,
since the kidneys filter the blood, it can
cause the urine to darken in color.
The bilirubin is also what colors our stools
when it reaches the intestines. Since it
is blocked…the stools will be a whitish
gray color and tend to float on top of the
toilet water because the fat hasn’t been
emulsified properly from the lack of
bile reaching it.
Gallstones are not the only things that
can cause biliary problems.
Any obstruction can. This would include
mal formation of the bile ducts or
strictures and twisting of those ducts
as occurs in sclerosing cholangitis.
Another thing is biliary cirrhosis. And
one more thing is an infection in the ducts.
A gallstone can also move down and
block the flow of bile, but also block
the pancreas duct also. Insulin is
produced by the pancreas. Insulin is
what causes the sugar to move into
our cells…without it, it will stay outside
the cell and become very high on
blood work. So, being this is the case:
I believe it might be a gallstone that
has blocked the flow of bile and also
is in the area where the pancreatic duct
connects just before going into the
intestines. However, some people with
liver problems do have a problem with
diabetes.

I hope this is of some help.

Beginnings and expansion of the auto-hemotherapy practice 2


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